Description

tert-Butyl 3-Bromo-5-formylbenzoate is a high-purity, multi-functional aromatic building block designed for advanced organic synthesis. This compound is valued for its dual reactive sites—the bromo and formyl groups—which enable sequential and selective functionalization, making it a critical intermediate for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, ligand synthesis, and the development of specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzoate or benzaldehyde motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where its halogen and aldehyde functionalities allow for diverse chemical modifications.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-organic frameworks (MOFs) and transition metal catalysts due to its ability to act as a chelating or bridging unit.
• Polymer and Material Science: Acts as a monomer or cross-linking agent in the synthesis of high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis via Suzuki-Miyaura coupling or reductive amination reactions.
• Fine Chemical Production: Utilized in the multi-step synthesis of dyes, pigments, and other complex aromatic fine chemicals.

Basic Information

Product Name	tert-Butyl 3-Bromo-5-formylbenzoate
CAS No.	1018948-99-6
Molecular Formula	C12H13BrO3
Molecular Weight	285.14 g/mol
Synonyms	3-Bromo-5-formylbenzoic acid tert-butyl ester; tert-Butyl 3-bromo-5-formylbenzoate; Benzoic acid, 3-bromo-5-formyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-bromo-5-formylbenzoate; 3-Bromo-5-[(tert-butoxy)carbonyl]benzaldehyde
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-5-formylbenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility meets the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.