Description

2-(Difluoromethyl)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block, offering unique reactivity for advanced chemical synthesis. Its value lies in the strategic incorporation of difluoromethyl groups, which can significantly alter the physical, chemical, and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the difluoromethyl group enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals with tailored electronic and optical properties.
• Fluorine Chemistry Research: A valuable reagent for studying the introduction and behavior of fluorinated motifs in complex molecular architectures.

Basic Information

Product Name	2-(Difluoromethyl)Benzaldehyde
CAS No.	1018678-50-6
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	o-(Difluoromethyl)benzaldehyde; 2-(Difluoromethyl)benzaldehyde; Benzaldehyde, 2-(difluoromethyl)-; 1-(Difluoromethyl)-2-formylbenzene; α,α-Difluoro-o-tolualdehyde
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethyl)Benzaldehyde is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP and ISO standards guarantees a reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.