Description

Ethyl 2-Oxo-2-[4-(Trifluoromethyl)Piperidino]Acetate is a high-value, fluorinated piperidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic incorporation of the trifluoromethyl group and the reactive keto-ester moiety, enabling the construction of complex molecular architectures with enhanced physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides that leverage the stability of the CF3 group.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or activity-based probes for target identification and validation.
• Material Science Research: Intermediate for synthesizing specialty monomers or ligands that impart unique characteristics to polymers and complexes.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects requiring precise fluorination and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 2-Oxo-2-[4-(Trifluoromethyl)Piperidino]Acetate
CAS No.	1017782-87-4
Molecular Formula	C10H14F3NO3
Molecular Weight	253.22 g/mol
Synonyms	Ethyl (4-(trifluoromethyl)piperidin-1-yl)oxoacetate; 2-Oxo-2-(4-(trifluoromethyl)-1-piperidinyl)acetic Acid Ethyl Ester; 1-Piperidineacetic acid, 4-(trifluoromethyl)-, α-oxo-, ethyl ester; Ethyl 2-(4-(trifluoromethyl)piperidin-1-yl)-2-oxoacetate; Acetic acid, 2-oxo-2-[4-(trifluoromethyl)-1-piperidinyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Oxo-2-[4-(Trifluoromethyl)Piperidino]Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.