Description

1-(3-Aminomethyl-Phenyl)-2-(4-Fluoro-Phenyl)-Ethanone is a high-purity, specialized organic intermediate featuring both an aminomethyl and a fluorinated aromatic ketone moiety. This unique bifunctional structure makes it a critical building block for the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive materials due to its conjugated system and functional handles.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	1-(3-Aminomethyl-Phenyl)-2-(4-Fluoro-Phenyl)-Ethanone
CAS No.	1017781-75-7
Molecular Formula	C15H14FNO
Molecular Weight	243.28 g/mol
Synonyms	3'-(Aminomethyl)-4-fluorobenzophenone; 1-[3-(Aminomethyl)phenyl]-2-(4-fluorophenyl)ethanone; 4-Fluoro-3'-aminomethylbenzophenone; 3-(Aminomethyl)-α-(4-fluorophenyl)acetophenone; α-(4-Fluorophenyl)-3-(aminomethyl)acetophenone; (3-Aminomethylphenyl)(4-fluorophenyl)methanone (tautomeric form); 1017781-75-7
EINECS	Contact for details

Quality Control

Every batch of 1-(3-Aminomethyl-Phenyl)-2-(4-Fluoro-Phenyl)-Ethanone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with specifications for key impurities available. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment. We support development projects with the capability to produce custom grades under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.