Description

1-(4-Aminomethyl-Phenyl)-2-(4-Fluoro-Phenyl)-Ethanone is a high-purity, specialized organic building block featuring both an aminomethyl and a fluorinated aromatic ketone moiety. This unique bifunctional structure makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the custom synthesis of complex dyes, pigments, and functional materials requiring specific aromatic ketone and amine functionalities.
• Bioconjugation and Probe Synthesis: The reactive aminomethyl group makes it suitable for creating fluorescent probes or bioconjugates for diagnostic and research applications.
• Academic and Contract Research: Essential compound for medicinal chemistry research and process development in academic and contract research organizations (CROs).

Basic Information

Product Name	1-(4-Aminomethyl-Phenyl)-2-(4-Fluoro-Phenyl)-Ethanone
CAS No.	1017781-71-3
Molecular Formula	C15H14FNO
Molecular Weight	243.28 g/mol
Synonyms	4'-(Aminomethyl)-4-fluorobenzophenone; 1-[4-(Aminomethyl)phenyl]-2-(4-fluorophenyl)ethanone; 4-Fluoro-α-(4-aminomethylphenyl)acetophenone; 4'-Aminomethyl-4-fluorobenzophenone; (4-Fluorophenyl)[4-(aminomethyl)phenyl]methanone; 1017781-71-3; 4-Fluoro-α-(4-aminomethylphenyl)acetophenone
EINECS	Contact for details

Quality Control

Our 1-(4-Aminomethyl-Phenyl)-2-(4-Fluoro-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of our clients. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.