Description

3-Chloro-4-(Trifluoromethoxy)-Phenylacetic Acid is a high-purity, synthetically valuable aromatic acid derivative featuring a unique trifluoromethoxy substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, creating compound libraries, and developing novel catalysts or ligands.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Item	Details
Product Name	3-Chloro-4-(Trifluoromethoxy)-Phenylacetic Acid
CAS No.	1017779-77-9
Molecular Formula	C9H6ClF3O3
Molecular Weight	254.59 g/mol
Synonyms	2-[3-Chloro-4-(trifluoromethoxy)phenyl]acetic Acid; (3-Chloro-4-(trifluoromethoxy)phenyl)acetic Acid; 3-Chloro-4-trifluoromethoxyphenylacetic Acid; α-(3-Chloro-4-(trifluoromethoxy)phenyl)acetic Acid; 1017779-77-9; 3-Chloro-4-(trifluoromethoxy)benzenacetic Acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-(Trifluoromethoxy)-Phenylacetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.