Description

1-(4-Chloro-3-Fluorophenyl)Propan-1-One is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogen substitution pattern enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a substrate for developing new synthetic methodologies in academic and industrial labs.
• Chemical Research: Utilized as a standard or reference compound in analytical and spectroscopic studies.

Basic Information

Product Name	1-(4-Chloro-3-Fluorophenyl)Propan-1-One
CAS No.	1017779-67-7
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	4'-Chloro-3'-Fluoropropiophenone; 1-Propanone, 1-(4-chloro-3-fluorophenyl)-; 3-Fluoro-4-chloropropiophenone; 4-Chloro-3-fluoropropiophenone; (4-Chloro-3-fluorophenyl)propan-1-one; 1-(4-Chloro-3-fluorophenyl)-1-propanone; 3'-Fluoro-4'-chloropropiophenone
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-3-Fluorophenyl)Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.