Description

3,5-Difluoro-2-Methylbenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, essential for advanced organic synthesis. Its unique difluoro-methyl substitution pattern makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as drug discovery and functional material development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Functional Material Precursor: Employed in the research and production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research (CRO/CMO): A valuable reagent for contract research and manufacturing organizations engaged in custom synthesis and scale-up projects.
• Fluorine Chemistry Studies: Used in academic and industrial labs to study structure-activity relationships (SAR) and the effects of fluorination on molecular properties.

Basic Information

Product Name	3,5-Difluoro-2-Methylbenzaldehyde
CAS No.	1017778-68-5
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2-Methyl-3,5-difluorobenzaldehyde; 3,5-Difluoro-o-tolualdehyde; 2-Methyl-3,5-difluorobenzenecarboxaldehyde; Benzaldehyde, 3,5-difluoro-2-methyl-; 1017778-68-5; 3,5-Difluoro-2-methyl-benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-2-Methylbenzaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and guarantee high chemical purity and lot-to-lot consistency, which is critical for your synthetic processes. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥97% by HPLC), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.