Description

3'-Ethoxy-2',4'-Difluoroacetophenone is a high-purity, specialized fluorinated aromatic ketone building block. This compound is valued for its unique molecular structure, which serves as a critical intermediate in advanced organic synthesis, particularly for introducing the difluoroethoxy phenyl moiety. It is primarily sought after by research and development teams and process chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine and ethoxy groups contribute to enhanced biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing specialty monomers and ligands used in catalysis and advanced polymer materials.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in cross-coupling reactions, fluorination chemistry, and the synthesis of complex heterocycles.
• Liquid Crystal & OLED Materials: A potential building block for creating fluorinated aromatic cores used in electronic display and lighting technologies.

Basic Information

Product Name	3'-Ethoxy-2',4'-Difluoroacetophenone
CAS No.	1017778-40-3
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	1-(2,4-Difluoro-3-ethoxyphenyl)ethanone; 2',4'-Difluoro-3'-ethoxyacetophenone; 3-Ethoxy-2,4-difluoroacetophenone; Ethanone, 1-(2,4-difluoro-3-ethoxyphenyl)-; Acetophenone, 2',4'-difluoro-3'-ethoxy-
EINECS	Contact for details

Quality Control

Every batch of 3'-Ethoxy-2',4'-Difluoroacetophenone is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical synthesis workflows. Our standard quality commitment includes HPLC purity ≥98.0% (typical), with detailed impurity profiling available. A Certificate of Analysis (COA) specifying identity, purity, and relevant physical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.