Description

2''-Methyl-3''-(Trifluoromethyl)Acetophenone is a high-purity, fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of a trifluoromethyl group can dramatically alter biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in fluorination chemistry and cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2''-Methyl-3''-(Trifluoromethyl)Acetophenone
CAS No.	1017778-01-6
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-(2-Methyl-3-(trifluoromethyl)phenyl)ethan-1-one; 2-Methyl-3-(trifluoromethyl)acetophenone; 2'-Methyl-3'-(trifluoromethyl)acetophenone; 1-(2-Methyl-3-(trifluoromethyl)phenyl)ethanone; 3-Trifluoromethyl-2-methylacetophenone; α,2-Dimethyl-α-(trifluoromethyl)benzeneacetaldehyde (tautomer); Acetophenone, 2'-methyl-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2''-Methyl-3''-(Trifluoromethyl)Acetophenone is produced and analyzed under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Standard purity is typically ≥97% (by HPLC), with specifications tailored to client requirements for R&D or scale-up projects. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.