Description

2-(2-Fluorophenyl)Ethanethioamide is a specialized fluorinated thioamide building block of significant interest in advanced organic synthesis and pharmaceutical research. Its core value lies in its unique molecular structure, which combines a fluorinated aromatic ring with a reactive thioamide group, making it a versatile precursor for constructing complex heterocycles and bioactive molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and insecticides, where the fluorine atom and thioamide moiety can enhance biological activity and environmental stability.
• Heterocyclic Chemistry: A crucial starting material for the construction of various nitrogen and sulfur-containing heterocycles, such as thiazoles, thiadiazoles, and fused ring systems, which are prevalent in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes in fine chemical synthesis.
• Material Science Precursor: Investigated for the synthesis of monomers and polymers with specific electronic or optical properties, leveraging the fluorine atom's influence on material characteristics.

Basic Information

Product Name	2-(2-Fluorophenyl)Ethanethioamide
CAS No.	1016739-02-8
Molecular Formula	C8H8FNS
Molecular Weight	169.22 g/mol
Synonyms	2-(2-Fluorophenyl)ethanethioamide; 2-Fluorophenethylthioamide; 2-(2-Fluorophenyl)ethanethioamide; 1-(2-Fluorophenyl)-2-thioxoethanamine; α-(2-Fluorophenyl)thioacetamide; 2-Fluoro-β-thioxobenzenepropanamide; 1016739-02-8
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)Ethanethioamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.