Description

1-Propanone, 2-Chloro-1-(4-Iodophenyl)- is a specialized halogenated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists working on novel active ingredients, where its unique structure allows for precise chemical modifications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of halogenated aromatic systems.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or optical properties.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and protein interactions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-Propanone, 2-Chloro-1-(4-Iodophenyl)-
CAS No.	1016718-94-7
Molecular Formula	C9H8ClIO
Molecular Weight	294.52 g/mol
Synonyms	2-Chloro-1-(4-iodophenyl)propan-1-one; 1-(4-Iodophenyl)-2-chloropropan-1-one; 4-Iodophenacyl Chloride; p-Iodophenacyl Chloride; 2-Chloro-1-(p-iodophenyl)ethanone (common misnomer); α-Chloro-4-iodoacetophenone; 4'-Iodo-2-chloroacetophenone
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2-Chloro-1-(4-Iodophenyl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.