Description

3-Chloro-4-(Difluoromethoxy)Benzene-1-Sulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its value lies in its dual reactive sites, the sulfonyl chloride and the halogenated aromatic ring, which enable precise molecular construction. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and advanced materials.
• Chemical Research: A versatile reagent for introducing the difluoromethoxy-phenyl-sulfonyl moiety into complex molecules in academic and industrial R&D.
• Dye and Pigment Manufacturing: Intermediate for creating specialized colorants and functional dyes.

Basic Information

Product Name	3-Chloro-4-(Difluoromethoxy)Benzene-1-Sulfonyl Chloride
CAS No.	1016714-35-4
Molecular Formula	C7H4Cl2F2O3S
Molecular Weight	277.07 g/mol
Synonyms	3-Chloro-4-(difluoromethoxy)benzenesulfonyl chloride; 4-(Difluoromethoxy)-3-chlorobenzenesulfonyl chloride; 1-Chloro-2-(difluoromethoxy)-5-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-chloro-4-(difluoromethoxy)-; 1016714-35-4
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-(Difluoromethoxy)Benzene-1-Sulfonyl Chloride adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the exacting standards required for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.