Description

3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzo[D]Oxazol-2(3H)-One is a high-value, organoboron-containing heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used to create new herbicides, fungicides, and insecticides by introducing the benzo[d]oxazolone-boronic ester moiety into lead structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in the development of advanced display and lighting technologies.
• Polymer & Material Science: Incorporated into specialty polymers and organic frameworks to modify physical properties, thermal stability, or electronic characteristics.
• Ligand & Catalyst Development: Utilized in the preparation of novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for target identification and validation.

Basic Information

Product Name	3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzo[D]Oxazol-2(3H)-One
CAS No.	1016641-53-4
Molecular Formula	C₁₆H₂₀BNO₄
Molecular Weight	301.15 g/mol
Synonyms	3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-benzoxazolinone; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-2(3H)-benzoxazolone; 3-Methyl-6-(pinacolatoboryl)-2-benzoxazolinone; 6-Pinacolatoboryl-3-methyl-2-benzoxazolinone; 1016641-53-4; Benzo[d]oxazol-2(3H)-one, 3-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 3-Methyl-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzo[D]Oxazol-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and production needs with material that meets the stringent standards required for GMP intermediates and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.