Description

2-Ethynyl-5-Fluorobenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its dual reactive sites—the aldehyde group and the terminal alkyne—enabling its use in sophisticated cross-coupling and cyclization reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic frameworks.
• Chemical Biology Probes: Utilized in click chemistry (e.g., CuAAC reactions) for labeling and studying biological systems due to its alkyne functionality.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing novel ligands used in asymmetric catalysis and metal-organic complexes.

Basic Information

Product Name	2-Ethynyl-5-Fluorobenzaldehyde
CAS No.	1015731-79-9
Molecular Formula	C9H5FO
Molecular Weight	148.14 g/mol
Synonyms	5-Fluoro-2-ethynylbenzaldehyde; 2-Ethynyl-5-fluorobenzaldehyde; 5-Fluoro-2-ethynylbenzenecarboxaldehyde; 2-Ethynyl-5-fluorobenzenecarbaldehyde; 1015731-79-9
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-5-Fluorobenzaldehyde is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.