Description

11 2-(Piperidin-1-yl)pyrimidine-5-boronic acid pinacol ester is a high-purity, advanced pharmaceutical intermediate belonging to the class of heterocyclic boronic acid pinacol esters. This compound is a critical building block in modern medicinal chemistry, enabling the efficient synthesis of complex molecules through key cross-coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex heterocyclic compounds.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of novel drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of new active ingredients for crop protection products.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized for the synthesis of molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services.

Basic Information

Product Name	11 2-(Piperidin-1-yl)pyrimidine-5-boronic acid pinacol ester
CAS No.	1015242-08-6
Molecular Formula	C15H22BN3O2
Molecular Weight	287.17 g/mol
Synonyms	2-(Piperidin-1-yl)pyrimidine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperidin-1-yl)pyrimidine; 2-Piperidin-1-yl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrimidine; 1015242-08-6; BRN 14219579; AKOS025247049; CS-0352695; FT-0778089
EINECS	Contact for details

Quality Control

Our 11 2-(Piperidin-1-yl)pyrimidine-5-boronic acid pinacol ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.