Description

1-Benzyl-4-[5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridin-2-Yl]Piperazine is a high-value, organoboron building block crucial for modern synthetic chemistry. This compound serves as a key intermediate in the synthesis of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the boronic ester functionality for efficient carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology Probes: Acts as a precursor for bioconjugation reagents and probes used in target identification and validation studies.
• Academic & Contract Research: Essential for methodology development and synthetic route exploration in university and CRO laboratories.
• Scale-up Process Development: Serves as a key starting material for process chemistry teams optimizing routes for clinical and commercial manufacturing.

Basic Information

Product Name	1-Benzyl-4-[5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridin-2-Yl]Piperazine
CAS No.	1015242-03-1
Molecular Formula	C22H30BN3O2
Molecular Weight	379.31 g/mol
Synonyms	1-Benzyl-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine; 2-(1-Benzylpiperazin-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1-Benzyl-4-(5-(pinacolatoboryl)pyridin-2-yl)piperazine; 5-(1-Benzylpiperazin-4-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Piperazinyl-5-(pinacolatoboryl)pyridine, N-Benzyl derivative; B-(6-(4-Benzylpiperazin-1-yl)pyridin-3-yl)boronic acid pinacol ester; CAS 1015242-03-1
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-[5-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridin-2-Yl]Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.