Description

2-(4-Cyclopentyl -Piperazin-1-Yl) Pyridine-5-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block featuring a boronic ester functional group. This compound is critically important for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex carbon-carbon bonds. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient formation of biaryl and other complex molecular architectures essential for drug discovery and development.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and herbicides.
• Material Science: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.

Basic Information

Product Name	2-(4-Cyclopentyl -Piperazin-1-Yl) Pyridine-5-Boronic Acid Pinacol Ester
CAS No.	1015242-01-9
Molecular Formula	C20H30BN3O2
Molecular Weight	355.29 g/mol
Synonyms	2-(4-Cyclopentylpiperazin-1-yl)pyridine-5-boronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(4-cyclopentylpiperazin-1-yl)pyridine; 2-(4-Cyclopentyl-1-piperazinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine-5-boronic acid, 2-(4-cyclopentyl-1-piperazinyl)-, pinacol ester; 1015242-01-9; Boronic acid, B-[2-(4-cyclopentyl-1-piperazinyl)-5-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-Cyclopentyl -Piperazin-1-Yl) Pyridine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical coupling reactions. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.