Description

(2-Methyl-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fused heterocyclic scaffolds found in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its ability to introduce the 2-methyl-1H-pyrrolo[2,3-b]pyridine moiety.
• Material Science: Serves as a precursor for creating functionalized organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological systems and enzyme inhibition.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl structures with high efficiency and selectivity.
• Library Synthesis: A valuable building block for generating diverse compound libraries in high-throughput screening for identifying new lead compounds.

Basic Information

Product Name	(2-Methyl-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Boronic Acid
CAS No.	1014614-07-3
Molecular Formula	C8H9BN2O2
Molecular Weight	175.98 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methyl-1H-pyrrolo[2,3-b]pyridine; (2-Methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)boronic acid; 2-Methyl-1H-pyrrolo[2,3-b]pyridine-4-boronic acid; 2-Methyl-4-borono-1H-pyrrolo[2,3-b]pyridine; 2-Methyl-1H-pyrrolo[2,3-b]pyridin-4-ylboronic acid; 4-Borono-2-methyl-1H-pyrrolo[2,3-b]pyridine; 1014614-07-3; 2-Methyl-1H-pyrrolo[2,3-b]pyridine-4-ylboronic acid pinacol ester.
EINECS	Contact for details

Quality Control

Our (2-Methyl-1H-Pyrrolo[2,3-B]Pyridin-4-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.