Description

Potassium 1H-Pyrazole-5-Trifluoroborate is an organotrifluoroborate salt, a versatile and stable building block in modern synthetic chemistry. Its value lies in its enhanced stability and handling properties compared to traditional boronic acids, making it a crucial reagent for Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrazole or related heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific pyrazole-based structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant organoboron reagent for palladium-catalyzed carbon-carbon bond formation in complex molecule assembly.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for various transition metal-mediated transformations.
• Material Science Research: A precursor for developing organic electronic materials, such as those used in OLEDs or conductive polymers, where the pyrazole moiety can modify electronic properties.
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules or creating chemical probes for biological target identification and validation.

Basic Information

Product Name	Potassium 1H-Pyrazole-5-Trifluoroborate
CAS No.	1013640-87-3
Molecular Formula	C3H3BF3KN2
Molecular Weight	173.97 g/mol
Synonyms	Potassium (1H-Pyrazol-5-yl)trifluoroborate; Potassium 1H-Pyrazol-5-yltrifluoroborate; 1H-Pyrazole-5-trifluoroborate Potassium Salt; 5-(Trifluoroborato)-1H-pyrazole Potassium Salt; Potassium 5-(Trifluoroboranyl)-1H-pyrazole; Pyrazole-5-trifluoroborate Potassium; Potassium Pyrazol-5-yltrifluoroborane
EINECS	Contact for details

Quality Control

Our Potassium 1H-Pyrazole-5-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available for every lot to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Assay (NMR/Titration)	≥90% (as potassium trifluoroborate salt)
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.