Description

Diethyl({[2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl})Amine is a specialized organoboron compound featuring a protected boronic acid ester and a tertiary amine functional group. This dual functionality makes it a versatile and valuable building block in advanced organic synthesis, particularly for the construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams, agrochemical researchers, and material scientists for applications in medicinal chemistry, catalyst development, and polymer science.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key arylboron reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common motif in active pharmaceutical ingredients (APIs).
• Medicinal Chemistry & Drug Discovery: Used as a versatile intermediate for constructing complex molecules in the search for new therapeutic agents, including kinase inhibitors and other small-molecule drugs.
• Agrochemical Intermediate: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl-amine structures.
• Ligand Synthesis for Catalysis: The amine group allows for the creation of novel bidentate or tridentate ligands used in transition metal catalysis.
• Functional Material Development: Acts as a monomer or precursor in the synthesis of organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Product Name	Diethyl({[2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl})Amine
CAS No.	1012785-46-4
Molecular Formula	C18H30BNO2
Molecular Weight	303.25 g/mol
Synonyms	2-((Diethylamino)methyl)phenylboronic acid pinacol ester; N,N-Diethyl-1-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanamine; [2-(Diethylaminomethyl)phenyl]boronic acid pinacol ester; (2-((Diethylamino)methyl)phenyl)boronic acid pinacol ester; Diethyl((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl))amine; B-(2-((Diethylamino)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Diethyl({[2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl})Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including NMR and HPLC, to verify identity and purity. Certificates of Analysis (COA) detailing specific lot results are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.