Description

4-Amino-1-(4-Methoxyphenyl)pyrrolidin-2-one hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and other specialty drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of compounds in structure-activity relationship (SAR) studies.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex target molecules for preclinical and clinical evaluation.
• Biochemical Research: Employed in studies investigating enzyme inhibition or receptor-ligand interactions due to its specific pyrrolidinone structure.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science and agrochemical research.

Basic Information

Product Name	4-Amino-1-(4-Methoxyphenyl)pyrrolidin-2-one hydrochloride
CAS No.	1011357-93-9
Molecular Formula	C11H15N2O2 • HCl
Molecular Weight	244.71 g/mol (Free base: 208.25 g/mol)
Synonyms	4-Amino-1-(4-methoxyphenyl)-2-pyrrolidinone hydrochloride; 1-(4-Methoxyphenyl)-4-aminopyrrolidin-2-one HCl; 4-Amino-1-(p-methoxyphenyl)pyrrolidin-2-one hydrochloride; 4-Amino-1-(4-methoxyphenyl)-2-pyrrolidone HCl; 1011357-93-9; 4-Amino-1-(4-methoxyphenyl)-2-oxopyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-1-(4-Methoxyphenyl)pyrrolidin-2-one hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.