Description

n-[(4-Fluorophenyl)Methyl]Carbamimidothioic Acid Methyl Ester is a specialized organofluorine thiourea derivative, serving as a critical synthetic intermediate in advanced chemical synthesis. Its molecular architecture, featuring both fluorophenyl and carbamimidothioate ester functionalities, makes it a valuable precursor for constructing complex molecules with targeted biological or material properties. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the fluorine atom and thiourea moiety are crucial for bioactivity and metabolic stability.
• Agrochemical Research: Used in the development of new-generation pesticides, herbicides, and fungicides, where its structure can contribute to improved efficacy and environmental profile.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes and labeled compounds used in biochemical assays and diagnostic research.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, ligands for catalysis, or advanced organic materials requiring specific fluorine-containing motifs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes under cGMP or research-grade conditions.

Basic Information

Product Name	n-[(4-Fluorophenyl)Methyl]Carbamimidothioic Acid Methyl Ester
CAS No.	1011347-39-9
Molecular Formula	C10H11FN2OS
Molecular Weight	226.27 g/mol
Synonyms	Methyl N-[(4-fluorophenyl)methyl]carbamimidothioate; 4-Fluorobenzyl Isothiourea Methyl Ester; Methyl (4-Fluorobenzyl)isothiourea; Carbamimidothioic acid, N-[(4-fluorophenyl)methyl]-, methyl ester; 1011347-39-9; Methyl (Z)-N-[(4-fluorophenyl)methyl]carbamimidothioate
EINECS	Contact for details

Quality Control

Our production of n-[(4-Fluorophenyl)Methyl]Carbamimidothioic Acid Methyl Ester adheres to stringent quality management protocols. Every batch is analytically verified using advanced techniques like HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality systems support delivery under research, technical, and custom synthesis grades to meet diverse project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.