Description

1-Bromo-3-Chloro-2-Ethoxy-Benzene is a high-purity halogenated aromatic ether building block designed for advanced organic synthesis. This compound is valued for its precise substitution pattern, which enables the controlled introduction of bromine and chlorine functionalities into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where specific halogen placement is critical for bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling complex bond formation.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Provides a versatile scaffold for further functionalization in multi-step synthetic routes across various R&D sectors.

Basic Information

Product Name	1-Bromo-3-Chloro-2-Ethoxy-Benzene
CAS No.	1010390-50-7
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	2-Bromo-6-Chloro-1-Ethoxybenzene; 3-Chloro-1-bromo-2-ethoxybenzene; Benzene, 1-bromo-3-chloro-2-ethoxy-; 1-Ethoxy-2-bromo-3-chlorobenzene; 2-Ethoxy-6-bromo-3-chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-2-Ethoxy-Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.