Description

2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value, multifunctional boronic ester derivative of salicylic acid, serving as a critical synthetic intermediate. Its core value proposition lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern organic synthesis for constructing complex biaryl and heterobiaryl scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing biphenyl or phenolic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with complex aromatic structures.
• Material Science: Precursor for organic electronic materials, including monomers for conductive polymers, OLEDs, and organic semiconductors.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated bidentate ligands used in catalysis.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new carbon-carbon bond-forming methodologies.
• Fluorescent Probe Synthesis: Used in the construction of boron-dipyrromethene (BODIPY) dyes and other fluorescent markers for bioimaging.

Basic Information

Product Name	2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	1009303-78-9
Molecular Formula	C13H17BO5
Molecular Weight	264.09 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-hydroxybenzoic acid; 2-Hydroxy-5-(pinacolatoboryl)benzoic acid; 5-(Pinacolatoboraneyl)-2-hydroxybenzoic acid; Salicylic acid-5-boronic acid pinacol ester; 5-Borono-2-hydroxybenzoic acid pinacol ester; 5-(Pinacolboron)salicylic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)salicylic acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.