Description

3-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid is a high-value, multifunctional chemical building block that combines a benzoic acid core with both an amino group and a boronic ester pinacol ester. This compound matters for its pivotal role as a key intermediate in modern synthetic chemistry, enabling the construction of complex molecules through versatile cross-coupling reactions. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aromatic boronic acid derivatives.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer & Material Science: Incorporated into the backbone of specialty polymers, covalent organic frameworks (COFs), and other advanced materials to impart specific functionality.
• Chemical Biology & Bioconjugation: Utilized in the development of probes, sensors, and bioconjugates due to the reactivity of the boronic ester and carboxylic acid groups.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for method development and exploratory synthesis projects.

Basic Information

Product Name	3-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid
CAS No.	1009094-73-8
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	3-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 5-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; Benzoic acid, 3-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Carboxy-5-aminophenylboronic acid pinacol ester; 3-Amino-5-borono-benzoic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-aminobenzoic acid; 3-Amino-5-Bpin-benzoic acid; Boric acid, B-[3-amino-5-(carboxyphenyl)]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.