Description

3-Hydroxy-2,3-Dimethylbutan-2-Yl Hydrogen (4'-Amino-[1,1'-Biphenyl]-4-Yl)Boronate is a specialized organoboron compound featuring a biphenyl amine moiety, serving as a crucial synthetic intermediate. Its value lies in its dual functionality, where the boronate ester group enables key cross-coupling reactions, and the aromatic amine provides a handle for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, particularly for constructing complex molecular architectures in drug discovery and organic electronics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological and oncological pathways.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for constructing biaryl and heterobiaryl structures central to many drug molecules.
• Organic Light-Emitting Diodes (OLEDs): Used in the development of electron-transport or emissive layer materials due to its stable, conjugated biphenyl core.
• Ligand Synthesis: Precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design of molecular probes and sensors that target specific biological processes.
• Polymer Chemistry: Monomer or chain-transfer agent for synthesizing functionalized polymers with tailored properties.

Basic Information

Product Name	3-Hydroxy-2,3-Dimethylbutan-2-Yl Hydrogen (4'-Amino-[1,1'-Biphenyl]-4-Yl)Boronate
CAS No.	1008788-39-3
Molecular Formula	C20H26BNO3
Molecular Weight	339.24 g/mol
Synonyms	Pinanediol (4'-Aminobiphenyl-4-yl)boronate; (4'-Amino-[1,1'-biphenyl]-4-yl)boronic acid pinacol ester; 2-(4'-Aminobiphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-[1,1'-biphenyl]-4-amine; 4'-Amino-4-biphenylboronic acid pinacol ester; (4'-Aminobiphenyl-4-yl)boronic acid, pinacol ester; B-[4-(4-Aminophenyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2,3-Dimethylbutan-2-Yl Hydrogen (4'-Amino-[1,1'-Biphenyl]-4-Yl)Boronate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.