Description

(Z)-(4-Hydroxy-2-Buten-2-Yl)Boronic Acid Pinacol Ester is a high-value, functionalized boronic ester building block crucial for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile organoboron reagent for palladium-catalyzed coupling with aryl/vinyl halides to create complex, functionalized olefinic structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Ligand and Catalyst Development: Employed in the preparation of novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A precursor for creating organic electronic materials, liquid crystals, and polymers with tailored properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	(Z)-(4-Hydroxy-2-Buten-2-Yl)Boronic Acid Pinacol Ester
CAS No.	1008752-03-1
Molecular Formula	C₁₀H₁₉BO₃
Molecular Weight	198.07 g/mol
Synonyms	(Z)-4-Hydroxybut-2-en-2-ylboronic acid pinacol ester; (Z)-1-(4-Hydroxybut-2-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (Z)-2-(4-Hydroxybut-2-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (Z)-4,4,5,5-Tetramethyl-2-(4-hydroxybut-2-en-2-yl)-1,3,2-dioxaborolane; (Z)-But-2-ene-2,4-diol, 2-boronic acid pinacol ester; (Z)-Vinylboronic acid pinacol ester, 4-hydroxy substituted
EINECS	Contact for details

Quality Control

Our (Z)-(4-Hydroxy-2-Buten-2-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and prolong shelf-life. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
(Z)-Isomer Content (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.