Description

(S)-tert-Butyl 3-Formylpiperidine-1-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) for the synthesis of complex bioactive molecules. Its value lies in providing a stereochemically defined, formyl-functionalized scaffold essential for constructing novel drug candidates, particularly in central nervous system (CNS) and antiviral research. This compound is primarily needed by pharmaceutical R&D laboratories, process chemistry teams, and CDMOs (Contract Development and Manufacturing Organizations) engaged in the development of innovative therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting neurological disorders and viral infections.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce the (S)-configured piperidine moiety into complex molecular architectures.
• Medicinal Chemistry Research: Serves as a versatile precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Development: The reactive aldehyde group enables its use in bioconjugation chemistry for creating diagnostic probes or targeted drug delivery systems.

Basic Information

Item	Details
Product Name	(S)-tert-Butyl 3-Formylpiperidine-1-Carboxylate
CAS No.	1008562-87-5
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(S)-1-Boc-3-formylpiperidine; (S)-3-Formyl-1-N-Boc-piperidine; (S)-N-Boc-3-piperidinecarboxaldehyde; (S)-tert-Butyl 3-formyl-1-piperidinecarboxylate; (S)-1-(tert-Butoxycarbonyl)-3-formylpiperidine; (S)-3-Carboxaldehyde-1-N-Boc-piperidine; (S)-Boc-3-formylpiperidine; (S)-3-Formylpiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-Formylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.