Description

2,3,3-Trifluoro-1,4-benzodioxen-5-ol is a high-value fluorinated benzodioxene derivative, serving as a critical synthetic intermediate and building block in advanced chemical synthesis. Its unique structure, featuring both a benzodioxene core and strategically placed fluorine atoms, makes it essential for modulating the electronic properties, metabolic stability, and lipophilicity of target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Development: Used in the research and synthesis of new-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand Synthesis: Utilized in organometallic chemistry for creating complex ligands used in catalysis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and novel fluorination reactions in academic and industrial R&D settings.

Basic Information

Product Name	2,3,3-Trifluoro-1,4-benzodioxen-5-ol
CAS No.	1008452-12-7
Molecular Formula	C9H5F3O3
Molecular Weight	218.13 g/mol
Synonyms	5-Hydroxy-2,3,3-trifluoro-1,4-benzodioxene; 2,3,3-Trifluoro-5-hydroxy-1,4-benzodioxine; 1,4-Benzodioxen-5-ol, 2,3,3-trifluoro-; 2,3,3-Trifluoro-1,4-benzodioxine-5-ol; 5-Hydroxy-2,3,3-trifluorobenzodioxole; TFBD-OH (abbreviation)
EINECS	Contact for details

Quality Control

Our 2,3,3-Trifluoro-1,4-benzodioxen-5-ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.