Description

4-Chloro-2-Methoxynicotinaldehyde is a versatile and high-purity chemical building block, essential for advanced organic synthesis and pharmaceutical research. Its unique structure, featuring both chloro and methoxy substituents on the pyridine ring, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science: Employed in the synthesis of functionalized heterocyclic compounds for advanced polymers and electronic materials.
• Chemical Biology: Utilized as a probe or labeling agent in bioconjugation chemistry and proteomics research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under GMP or ISO guidelines.

Basic Information

Product Name	4-Chloro-2-Methoxynicotinaldehyde
CAS No.	1008451-58-8
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	4-Chloro-2-methoxypyridine-3-carbaldehyde; 3-Formyl-4-chloro-2-methoxypyridine; 4-Chloro-2-methoxy-3-pyridinecarboxaldehyde; 2-Methoxy-4-chloronicotinaldehyde; 4-Chloro-2-methoxynicotinaldehyde; 1008451-58-8; 4-Chloro-2-methoxy-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methoxynicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development under ISO and cGMP frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.