Description

4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Naphthalene-1-Carbaldehyde is a high-value, multi-functional organic building block that combines a naphthalene aldehyde moiety with a protected boronic ester group. This compound matters for its critical role as a versatile intermediate in modern synthetic chemistry, enabling the construction of complex molecular architectures through cross-coupling and subsequent functionalization reactions. Pharmaceutical, agrochemical, and advanced materials researchers need this chemical for developing novel active ingredients, organic electronic materials, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex, bioactive molecules for next-generation herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host molecules in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for asymmetric catalysis and transition metal complexes.
• Polymer and Material Science: Incorporated into the backbone of conjugated polymers for organic photovoltaics (OPVs) and other electronic applications.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Academic and R&D: Essential reagent for methodological development in organic synthesis and materials research laboratories.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Naphthalene-1-Carbaldehyde
CAS No.	1008361-71-4
Molecular Formula	C₁₇H₁₉BO₃
Molecular Weight	282.14 g/mol
Synonyms	1-Naphthalenecarboxaldehyde, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthaldehyde; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene-1-carboxaldehyde; 4-Pinacolatoboryl-1-naphthaldehyde; 1-Formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 4-Boronic acid pinacol ester naphthalene-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Naphthalene-1-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.