Description

(S)-2-[5-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Imidazol-2-Y is a high-purity, chiral boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through cross-coupling reactions, particularly Suzuki-Miyaura couplings. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in advanced materials science for creating functional organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides with specific chiral activity.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for constructing biaryl and heterobiaryl structures under mild conditions.
• Ligand and Catalyst Development: Building block for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and drug discovery.

Basic Information

Product Name	(S)-2-[5-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Imidazol-2-Y
CAS No.	1007882-12-3
Molecular Formula	C20H26BN2O2
Molecular Weight	337.25 g/mol
Synonyms	(S)-2-(5-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine; (S)-2-[5-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazol-2-yl]pyrrolidine; (S)-2-(5-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-imidazol-2-yl)pyrrolidine; 1H-Imidazole, 2-[(2S)-2-pyrrolidinyl]-5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; (S)-2-(5-(4-(Pinacolatoboryl)phenyl)-1H-imidazol-2-yl)pyrrolidine; (S)-2-(5-(4-Borono-phenyl)-1H-imidazol-2-yl)pyrrolidine pinacol ester
EINECS	Contact for details

Quality Control

Our (S)-2-[5-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-1H-Imidazol-2-Y is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.