Description

4-Pentenoic Acid, 2-[(Methoxycarbonyl)Amino]-, (2S)- is a chiral, non-natural amino acid derivative featuring a reactive pentenoic acid backbone and a urethane-protected amine group. This compound is a high-value synthetic intermediate prized for its versatility in constructing complex, biologically active molecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of peptide mimetics, enzyme inhibitors, and other advanced therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics Research: Used to incorporate constrained, unsaturated moieties into peptide backbones, enhancing metabolic stability and modulating conformational properties.
• Chemical Biology Probes: Serves as a precursor for synthesizing activity-based probes and labeled compounds for studying enzyme function and mechanism.
• Asymmetric Synthesis: Employed in stereoselective reactions, such as conjugate additions or cyclizations, to construct complex chiral centers in natural product synthesis.
• Ligand Development: Utilized in the creation of specialized ligands for catalysis or molecular recognition applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, optically pure intermediates.

Basic Information

Item	Detail
Product Name	4-Pentenoic Acid, 2-[(Methoxycarbonyl)Amino]-, (2S)-
CAS No.	1007880-15-0
Molecular Formula	C8H13NO4
Molecular Weight	187.19 g/mol
Synonyms	(2S)-2-[(Methoxycarbonyl)amino]-4-pentenoic acid; L-2-[(Methoxycarbonyl)amino]-4-pentenoic acid; (S)-2-((Methoxycarbonyl)amino)pent-4-enoic acid; N-Carbomethoxy-L-2-amino-4-pentenoic acid; N-Methoxycarbonyl-L-2-amino-4-pentenoic acid; (S)-N-Methoxycarbonyl-2-amino-4-pentenoic acid; (S)-2-(Methoxycarbonylamino)pent-4-enoic acid; CAS 1007880-15-0
EINECS	Contact for details

Quality Control

Our production of 4-Pentenoic Acid, 2-[(Methoxycarbonyl)Amino]-, (2S)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and titration for assay determination, to ensure compliance with exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, guaranteeing traceability and consistency for your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.