Description

4,4,5,5-Tetramethyl-2-[4-(Thien-2-Ylmethyl)Phenyl]-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research: A versatile reagent in academic and industrial R&D labs for methodology development and the synthesis of complex organic molecules.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Polymer Chemistry: Can be incorporated into polymer backbones to modify material properties like conductivity or luminescence.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[4-(Thien-2-Ylmethyl)Phenyl]-1,3,2-Dioxaborolane
CAS No.	1007847-76-8
Molecular Formula	C17H21BO2S
Molecular Weight	300.22 g/mol
Synonyms	2-[4-(2-Thienylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(4-((thiophen-2-yl)methyl)phenyl)-1,3,2-dioxaborolane; 4-(Thien-2-ylmethyl)phenylboronic acid pinacol ester; [4-(2-Thienylmethyl)phenyl]boronic acid pinacol ester; Pinacol [4-(thiophen-2-ylmethyl)phenyl]boronate; (4-((Thiophen-2-yl)methyl)phenyl)boronic acid pinacol ester; CAS 1007847-76-8
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[4-(Thien-2-Ylmethyl)Phenyl]-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.