Description

Ethyl 5-(4-(4-(3,5-Dimethylisoxazole-4-Carbonyl)Piperazin-1-Yl)Phenyl)-1-o-Tolyl-1H-Pyrazole-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists exploring novel therapeutic agents, particularly in kinase inhibitor and targeted oncology programs. Its complex heterocyclic structure makes it a valuable building block for synthesizing potent and selective drug candidates in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel small-molecule drug candidates, particularly for oncology and anti-inflammatory targets.
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective kinase inhibitors due to its pyrazole and isoxazole motifs.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening and biochemical assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to research organizations and manufacturers for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	Ethyl 5-(4-(4-(3,5-Dimethylisoxazole-4-Carbonyl)Piperazin-1-Yl)Phenyl)-1-o-Tolyl-1H-Pyrazole-3-Carboxylate
CAS No.	1007477-05-5
Molecular Formula	C29H31N5O4
Molecular Weight	513.59 g/mol
Synonyms	Ethyl 1-(2-methylphenyl)-5-[4-[4-(3,5-dimethyl-1,2-oxazole-4-carbonyl)piperazin-1-yl]phenyl]-1H-pyrazole-3-carboxylate; 1H-Pyrazole-3-carboxylic acid, 5-[4-[4-(3,5-dimethyl-4-isoxazolyl)carbonyl]-1-piperazinyl]phenyl]-1-(2-methylphenyl)-, ethyl ester; UNII-7K0F2JN5UJ; 1007477-05-5; Ethyl 5-(4-(4-(3,5-dimethylisoxazole-4-carbonyl)piperazin-1-yl)phenyl)-1-(o-tolyl)-1H-pyrazole-3-carboxylate; 7K0F2JN5UJ; SCHEMBL15450497
EINECS	Contact for details

Quality Control

Our Ethyl 5-(4-(4-(3,5-Dimethylisoxazole-4-Carbonyl)Piperazin-1-Yl)Phenyl)-1-o-Tolyl-1H-Pyrazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.