Description

2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)benzo[d]thiazole is a high-value, advanced pharmaceutical intermediate and organic building block featuring a benzothiazole core linked to a pinacol boronate ester. This compound matters for its critical role in modern synthetic chemistry, specifically in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures essential for drug discovery and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those containing benzothiazole or biaryl motifs with potential biological activity.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester group serves as a versatile handle for palladium-catalyzed carbon-carbon bond formation with aryl halides.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring complex aromatic architectures.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport or host materials in OLED devices due to the benzothiazole moiety's electronic properties.
• Ligand and Catalyst Development: The nitrogen and sulfur atoms in the benzothiazole ring can coordinate to metals, making it useful for developing new catalytic systems.
• Polymer and Material Science: Employed to incorporate functional aromatic units into polymers for advanced materials with specific optical or electronic characteristics.

Basic Information

Item	Details
Product Name	2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)benzo[d]thiazole
CAS No.	1007375-81-6
Molecular Formula	C21H22BNO2S
Molecular Weight	363.28 g/mol
Synonyms	2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-benzothiazole; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzothiazole; 2-(4-Pinacolatoboronphenyl)benzothiazole; 4-(Benzothiazol-2-yl)phenylboronic acid pinacol ester; Benzo[d]thiazole, 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 1007375-81-6; BTH-BPin
EINECS	Contact for details

Quality Control

Our production of 2-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)benzo[d]thiazole adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications like pharmaceutical R&D. All materials are characterized by advanced analytical techniques including HPLC, NMR (1H and 13C), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronate ester. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.