Description

tert-Butyl 1-(4-Formylphenyl)-1-Oxo-5,8,11-Trioxa-2-Azatridecan-13-Oate is a high-purity, synthetic organic compound featuring a benzaldehyde core linked to a polyether chain terminated with a tert-butyl ester, making it a valuable PEGylated linker and building block for advanced chemical synthesis. Its bifunctional design, containing both a reactive aldehyde and a protected carboxylic acid, is critical for creating customizable molecular architectures with tailored solubility and pharmacokinetic properties. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for developing prodrugs, targeted drug delivery systems, and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Prodrug Development: Used to create linker systems that connect active pharmaceutical ingredients (APIs) to solubilizing or targeting moieties.
• Bioconjugation Chemistry: The aldehyde group enables site-specific conjugation to proteins, peptides, or antibodies via oxime or hydrazone formation.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating PEG-based hydrogels and smart materials.
• Chemical Biology Probes: Facilitates the development of fluorescent or affinity tags for studying biological processes.
• Custom Synthesis & Research: Provides a versatile scaffold for medicinal chemistry and organic synthesis research programs.

Basic Information

Product Name	tert-Butyl 1-(4-Formylphenyl)-1-Oxo-5,8,11-Trioxa-2-Azatridecan-13-Oate
CAS No.	1007215-94-2
Molecular Formula	C24H37NO7
Molecular Weight	451.56 g/mol
Synonyms	4-Formyl-N-(13-(tert-butoxy)-13-oxo-3,6,9-trioxa-12-azatridecyl)benzamide; tert-Butyl 3,6,9-trioxa-12-azatridecan-13-oate, 12-[(4-formylbenzoyl)amino]-; PEG3-t-butyl ester aldehyde linker; 4-Formylbenzoyl-PEG3-t-butyl ester; Fmoc-PEG3-CH2CH2COOH-t-butyl ester aldehyde derivative; Aldehyde-PEG3-acid t-butyl ester; N-(4-Formylbenzoyl)-3,6,9-trioxa-12-azatridecan-13-oic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 1-(4-Formylphenyl)-1-Oxo-5,8,11-Trioxa-2-Azatridecan-13-Oate is produced under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for research and cGMP manufacturing. Certificates of Analysis (COA) with detailed specifications are available upon request for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.