Description

(3-Bromo-4-Fluorophenyl)(Morpholino)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic bromo-fluoro substitution pattern linked to a morpholine carbonyl group. This molecular architecture makes it a critical building block for medicinal chemists, enabling the synthesis of novel bioactive compounds. It is primarily utilized in research and development for creating potential drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the bioactivity of the halogenated phenyl moiety.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aromatic fragments into molecular scaffolds.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(3-Bromo-4-Fluorophenyl)(Morpholino)Methanone
CAS No.	1007207-89-7
Molecular Formula	C11H11BrFNO2
Molecular Weight	288.12 g/mol
Synonyms	Morpholino(3-bromo-4-fluorophenyl)methanone; 3-Bromo-4-fluorophenyl morpholino ketone; 4-Morpholinyl(3-bromo-4-fluorophenyl)methanone; (3-Bromo-4-fluorobenzoyl)morpholine; 1007207-89-7; 3-Bromo-4-fluoro-N-morpholinobenzamide
EINECS	Contact for details

Quality Control

Our (3-Bromo-4-Fluorophenyl)(Morpholino)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.