Description

1H-Benzimidazole-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development.

Application

• Pharmaceutical Intermediates: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing benzimidazole scaffolds.
• Agrochemical Research: Used in the development of new fungicides, herbicides, and plant growth regulators requiring specific heterocyclic structures.
• Material Science: Building block for creating organic electronic materials, such as OLEDs and conductive polymers, where precise molecular design is crucial.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for target identification and validation studies.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions for clinical trials.

Basic Information

Product Name	1H-Benzimidazole-5-Boronic Acid, Pinacol Ester
CAS No.	1007206-54-3
Molecular Formula	C13H17BN2O2
Molecular Weight	244.10 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole; Benzimidazole-5-boronic acid pinacol ester; 1H-Benzo[d]imidazol-5-ylboronic acid pinacol ester; 5-(Pinacolatoboryl)-1H-benzimidazole; 5-Borono-1H-benzimidazole, pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.