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N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-1-Amine CAS NO 1007126-41-1
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CAS No.:1007126-41-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-1-Amine is a high-value, functionalized naphthalene derivative containing a pinacol boronate ester group. This compound serves as a critical advanced pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent, enabling the construction of complex organic frameworks. It is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and organic electronics who require precise, high-purity building blocks for drug discovery and material science.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
- Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic ester reagent for forming carbon-carbon bonds to create biaryl structures common in advanced materials and drugs.
- Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of electron-transport or host materials for display and lighting technologies.
- Agrochemical Synthesis: Intermediate for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
- Ligand and Catalyst Development: Serves as a precursor for synthesizing novel ligands used in catalytic systems and metal-organic frameworks (MOFs).
- Chemical Research & Development: A valuable tool for medicinal chemists and process chemists exploring new synthetic pathways and molecular architectures.
Basic Information
| Item | Details |
|---|---|
| Product Name | N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-1-Amine |
| CAS No. | 1007126-41-1 |
| Molecular Formula | C18H24BNO2 |
| Molecular Weight | 297.20 g/mol |
| Synonyms | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylnaphthalen-1-amine; 1-(Dimethylamino)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; N,N-Dimethyl-1-naphthylamine-4-boronic acid pinacol ester; 1-Dimethylamino-4-naphthaleneboronic acid pinacol ester; 4-(Dimethylamino)-1-naphthaleneboronic acid pinacol ester; N,N-Dimethyl-4-(pinacolatoboryl)-1-naphthylamine |
| EINECS | Contact for details |
Quality Control
Our N,n-Dimethyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-1-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency suitable for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% (Area %) |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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