Description

2-(4-Bromo-3-Methyl-1H-Pyrazol-1-Yl)-2-Methylpropanoic Acid is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo-substituted pyrazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent discovery.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, including herbicides and fungicides, leveraging its halogenated heterocyclic structure.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of functionalized ligands for metal-organic frameworks (MOFs) or advanced polymers.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, high-value brominated pyrazole carboxylic acid derivatives.

Basic Information

Product Name	2-(4-Bromo-3-Methyl-1H-Pyrazol-1-Yl)-2-Methylpropanoic Acid
CAS No.	1006473-56-8
Molecular Formula	C8H11BrN2O2
Molecular Weight	247.09 g/mol
Synonyms	2-(4-Bromo-3-methyl-1H-pyrazol-1-yl)-2-methylpropanoic acid; 2-Methyl-2-[(4-bromo-3-methyl-1H-pyrazol-1-yl)]propanoic Acid; 2-(4-Bromo-3-methylpyrazol-1-yl)-2-methylpropionic Acid; α-(4-Bromo-3-methyl-1H-pyrazol-1-yl)isobutyric Acid; 4-Bromo-3-methyl-1H-pyrazole-1-acetic acid, α,α-dimethyl-; 1006473-56-8; 2-(4-Bromo-3-methyl-1H-pyrazol-1-yl)-2-methylpropionic acid
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-3-Methyl-1H-Pyrazol-1-Yl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.