Description

1H-Pyrazole-3-Carboxylic Acid, 4-Bromo-1-(1-Methylethyl)- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazole core enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its bioactive pyrazole scaffold.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylic Acid, 4-Bromo-1-(1-Methylethyl)-
CAS No.	1006451-37-1
Molecular Formula	C7H9BrN2O2
Molecular Weight	233.07 g/mol
Synonyms	4-Bromo-1-isopropyl-1H-pyrazole-3-carboxylic acid; 1-Isopropyl-4-bromo-1H-pyrazole-3-carboxylic acid; 4-Bromo-1-(propan-2-yl)-1H-pyrazole-3-carboxylic acid; 4-Bromo-1-isopropylpyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 4-bromo-1-(1-methylethyl)-; 1006451-37-1; 4-Br-1-iPr-pyrazole-3-COOH
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carboxylic Acid, 4-Bromo-1-(1-Methylethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided for each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.