Description

1-[1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl]Ethanone is a high-value trifluoromethylpyrazole derivative, a key structural motif prized for its ability to modulate the physicochemical and biological properties of target molecules. This compound serves as a critical synthetic intermediate, enabling the development of advanced materials and active ingredients with enhanced stability and performance. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group contributes to improved lipophilicity, metabolic stability, and biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials that require specific fluorinated components for desired thermal and electronic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or tagging agent in the design of chemical probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing for client-specific molecule development.

Basic Information

Product Name	1-[1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl]Ethanone
CAS No.	1006434-30-5
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	5-Acetyl-1-methyl-3-(trifluoromethyl)-1H-pyrazole; 1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl ethanone; 5-Acetyl-1-methyl-3-trifluoromethylpyrazole; 1-Methyl-3-trifluoromethyl-1H-pyrazol-5-yl methyl ketone; 3-(Trifluoromethyl)-1-methyl-1H-pyrazol-5-yl ethanone; Ethanone, 1-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-; 1-(1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-[1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl]Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.