Description

(S)-2-(3,4-Difluorophenyl)Oxirane is a high-value chiral epoxide building block of significant importance in modern synthetic chemistry. Its core value lies in its stereochemically defined oxirane ring, which serves as a versatile electrophilic handle for the synthesis of complex, optically active molecules. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the construction of novel active ingredients, where the (S)-configuration and the difluorophenyl moiety are critical for biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, CNS agents, and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluorophenyl group enhances lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring enantiomerically pure epoxide chemistry.

Basic Information

Product Name	(S)-2-(3,4-Difluorophenyl)Oxirane
CAS No.	1006376-63-1
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	(S)-3,4-Difluorostyrene oxide; (S)-2-(3,4-Difluorophenyl)oxirane; (S)-1,2-Epoxy-2-(3,4-difluorophenyl)ethane; (S)-3,4-Difluoro-α,β-epoxystyrene; (S)-2-(3,4-Difluorophenyl)ethylene oxide; (S)-DFSO; (S)-(-)-2-(3,4-Difluorophenyl)oxirane
EINECS	Contact for details

Quality Control

Our (S)-2-(3,4-Difluorophenyl)Oxirane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with stringent R&D and cGMP standards where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.