Description

4-Fluoro-3-Formylbenzamide is a high-purity, multi-functional organic intermediate characterized by its reactive formyl and amide groups on a fluorinated aromatic ring. This compound matters for its critical role in facilitating the synthesis of complex molecules, offering a precise building block for advanced chemical research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced material scientists for constructing active pharmaceutical ingredients (APIs), novel crop protection agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the production of advanced polymers and liquid crystals where the fluorine moiety imparts desired thermal and chemical resistance.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for diagnostic and research applications.
• Custom Synthesis & Scale-Up: An essential substrate for contract research organizations (CROs) and CDMOs performing custom synthesis from milligram to kilogram scale.

Basic Information

Product Name	4-Fluoro-3-Formylbenzamide
CAS No.	1005763-14-3
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	3-Formyl-4-fluorobenzamide; 4-Fluoro-3-formyl-benzamide; Benzamide, 4-fluoro-3-formyl-; 4-Fluoroisophthalamide aldehyde; 1005763-14-3; 4-Fluoro-3-carbamoylbenzaldehyde; 3-Carbamoyl-4-fluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Formylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.