Description

1H-Indazole-5-Carbohydrazide is a high-purity heterocyclic building block and key synthetic intermediate. This compound is valued for its versatile reactivity, particularly in the formation of hydrazone linkages and heterocyclic ring systems. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Its specific structure makes it a critical component in medicinal chemistry programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with indazole-based scaffolds for oncology, CNS, and metabolic disease research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for constructing complex molecules, including fused heterocycles.
• Material Science: Potential use in the development of specialty polymers, ligands for catalysis, and advanced organic materials.
• Bioconjugation & Probe Development: The carbohydrazide functional group is useful for bioconjugation chemistry, enabling the creation of labeled probes for diagnostic applications.

Basic Information

Product Name	1H-Indazole-5-Carbohydrazide
CAS No.	1005205-25-3
Molecular Formula	C8H8N4O
Molecular Weight	176.18 g/mol
Synonyms	1H-Indazole-5-carboxylic acid hydrazide; 5-Hydrazinylcarbonyl-1H-indazole; Indazole-5-carbohydrazide; 5-Carbohydrazide-1H-indazole; 1H-Indazole-5-carboxyhydrazide; 5-Indazolecarbohydrazide; 1005205-25-3 (CAS); 1H-Indazol-5-ylcarbohydrazide
EINECS	Contact for details

Quality Control

Our 1H-Indazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.