Description

2-Benzyloxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anisole is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aromatic and heteroaromatic scaffolds.
• Agrochemical Synthesis: Used to construct novel fungicides, herbicides, and insecticides through palladium-catalyzed coupling reactions.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating advanced organic electronic materials, including charge-transport layers and emissive compounds.
• Polymer & Specialty Chemical Manufacturing: Enables the incorporation of specific aromatic units into polymers and specialty chemicals to tailor properties like thermal stability and optical characteristics.
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic research and contract research organizations (CROs).
• Chemical Biology & Probe Development: Used to synthesize molecular probes and tools for studying biological processes and target engagement.

Basic Information

Item	Details
Product Name	2-Benzyloxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Anisole
CAS No.	1005010-03-6
Molecular Formula	C20H25BO4
Molecular Weight	340.22 g/mol
Synonyms	4-(Benzyloxy)-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-(phenylmethoxy)benzeneboronic acid pinacol ester; (4-(Benzyloxy)-2-methoxyphenyl)boronic acid pinacol ester; 2-Benzyloxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anisole; 4-Benzyloxy-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-benzyloxyphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the boronic ester group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.