Description

4,4,5,5-Tetramethyl-2-(Thieno[3,2-B]Thiophen-2-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is critically needed by researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries for developing novel active ingredients and functional materials. Its specific structure offers unique reactivity and stability profiles for demanding synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Organic Electronic Materials: Crucial monomer for constructing conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic frameworks.
• Material Science Research: Serves as a precursor for creating novel organic semiconductors, liquid crystals, and other functional materials with tailored electronic properties.
• Chemical Biology & Diagnostics: Employed in the synthesis of probes, sensors, and labeled compounds for biological imaging and assay development.
• Catalyst & Ligand Development: Acts as a synthetic handle for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(Thieno[3,2-B]Thiophen-2-Yl)-1,3,2-Dioxaborolane
CAS No.	1004784-50-2
Molecular Formula	C14H17BO2S2
Molecular Weight	292.22 g/mol
Synonyms	2-(Thieno[3,2-b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Thieno[3,2-b]thiophene-2-boronic acid pinacol ester; 2-(Thieno[3,2-b]thiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; TTBD; Thienothiophene pinacol boronate ester; 2-(Thieno[3,2-b]thiophene-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 4,4,5,5-Tetramethyl-2-(Thieno[3,2-B]Thiophen-2-Yl)-1,3,2-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications like pharmaceutical R&D. Each lot undergoes comprehensive analysis using advanced techniques including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.