Description

Methyl 1-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Cyclopropane-1-Carboxylate is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a key building block in modern organic synthesis, particularly for cross-coupling reactions. It is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular scaffolds for constructing complex target molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal boron-containing reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Utilized in the design and synthesis of molecular probes and drug candidates for biological screening.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring functionalized cyclopropane and arylboronate motifs.

Basic Information

Item	Detail
Product Name	Methyl 1-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Cyclopropane-1-Carboxylate
CAS No.	1004294-83-0
Molecular Formula	C17H23BO4
Molecular Weight	302.18 g/mol
Synonyms	3-(1-Methoxycarbonylcyclopropyl)phenylboronic acid pinacol ester; Methyl 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarboxylate; 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarboxylic acid methyl ester; 3-(Methoxycarbonylcyclopropyl)phenylboronic acid pinacol ester; (3-(1-(Methoxycarbonyl)cyclopropyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Methyl 1-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Cyclopropane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for all shipments. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.